The best acne medication differs from person to person based on their skin care needs. For some, a gentle over-the-counter option is the best way to reduce acne, while for others, stronger prescription medication is necessary. Regardless of your acne needs, there is an acne medication available for you. The best way to find the right acne treatment is with patience, and sometimes with the assistance of a dermatologist. This guide will cover the basics of acne medication, from benzoyl peroxide to Accutane.
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Unfortunately, the vast majority of acne products are formulated incorrectly and/or made with cheap ingredients. Even dermatologists get it wrong and you shouldn’t assume that a treatment system is good for you just because dermatologists or celebrities say so online. They are most likely paid for their testimonial. Instead, make an effort to find out what the actual users of the products are saying. Amazon is a great place to start.
Oral antibiotics are recommended for no longer than three months as antibiotic courses exceeding this duration are associated with the development of antibiotic resistance and show no clear benefit over shorter courses.[87] Furthermore, if long-term oral antibiotics beyond three months are thought to be necessary, it is recommended that benzoyl peroxide and/or a retinoid be used at the same time to limit the risk of P. acnes developing antibiotic resistance.[87]
Retinoids: Retinoids are substances that are derived from vitamin A, which includes retinol, but also includes synthetic versions of retinol with activated retinoic acid which tends to be more effective in treating acne. Retinoic acid has been shown to reduce sebum production8 and regulate skin cell production9, which together can greatly reduce acne. These synthetic retinoids include adapalene, tretinoin, isotretinoin, and others. Although these synthetic options are more reliably effective, they also tend to have more side effects, like burning, itching, and dryness. Unlike retinol, which is available over-the-counter, nearly all synthetic retinoids are prescription-only. One of the main exceptions is Differin, which is a brand that sells a topical gel containing adapalene, a mild synthetic retinoid, over-the-counter.
Keep in mind that even if some products market themselves toward severe acne breakouts, all the kits we looked at are definitely designed for mild to moderate acne. Not sure if you fit on that scale? You’re not alone! When you’re in the middle of a breakout, all acne seems severe, so it can be difficult to self-diagnose your symptoms. We talked to dermatologists and cosmetic chemists to better understand the differences between the various types of acne (see below).
Meanwhile, salicylic acid, which is derived from willow tree bark, wintergreen oil or sweet birch and occurs naturally in fruits like raspberries, cantaloupe and granny smith apples, works well for most skin types. Aside from being an exfoliant that sloughs away dead skin cells and other pore-clogging impurities, it has anti-inflammatory properties that help to address inflammation, which is thought to be the primary cause of acne.
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You really don’t need to pay more than $25 per month to get the best acne treatment system. Systems priced higher than that are, in our opinion, overpriced. Unless you have serious types of acne that require medical attention, it’s better to stay out of the dermatologists office. It’s inconvenient, expensive, potentially uncomfortable (think side-effects from medication), and no more effective than a good, complete acne treatment system you can use at home. Finally, you can go cheaper and treat your acne with homemade remedies. But the treatment experience and the results are very unlikely to be as good as they are with a treatment system.

Postinflammatory hyperpigmentation (PIH) is usually the result of nodular acne lesions. These lesions often leave behind an inflamed darkened mark after the original acne lesion has resolved. This inflammation stimulates specialized pigment-producing skin cells (known as melanocytes) to produce more melanin pigment which leads to the skin's darkened appearance.[34] People with darker skin color are more frequently affected by this condition.[35] Pigmented scar is a common term used for PIH, but is misleading as it suggests the color change is permanent. Often, PIH can be prevented by avoiding any aggravation of the nodule, and can fade with time. However, untreated PIH can last for months, years, or even be permanent if deeper layers of skin are affected.[36] Even minimal skin exposure to the sun's ultraviolet rays can sustain hyperpigmentation.[34] Daily use of SPF 15 or higher sunscreen can minimize such a risk.[36]

You will see the results from the top performers in the comparison chart. Although any of these treatment systems can safely and effectively help reduce blemishes, Exposed Skin Care stands above the rest as the best acne treatment system. All the products are safe and regulated by the FDA, but Exposed Skin Care also works for a variety of skin types, including sensitive skin. The thing we like most about Exposed Skin Care is the 6-month money back guarantee. Many blemish products expect you to use them for six to eight weeks before you see results and then only provide you with a 1-month guarantee. If you purchase individual products in the store, you are stuck with them, since many do not come with any guarantees. Exposed Skin Care allows you to give their product a fair trial before you decide if it is working for your skin.
The acne companies that actually care about you, honest companies, offer a solid guarantee and honor it when necessary! A guarantee is a measure of the confidence a company has that their products will actually make a positive difference to your skin. Check Amazon and Google to see what people say about a company’s customer care before you buy. It’s the only way to know for sure what to expect before you buy from a certain company.

The third phase of the life cycle of acne is inflammation. At this point, your body’s immune system may deal with the problem, but if it doesn’t, different bacteria can move into the pore. Detecting an enemy bacterial invader, your body responds by emitting white blood cells to the infected area. In some cases, the white blood cells have a difficult time fighting the bacteria, and some die, contributing to the oily buildup and creating pus.


Considerations: Despite the frequent referencing of an initial flare of acne when starting is tretinoin, there is no scientific evidence to back this up. You should not expect an initial worsening of acne.3-4 Exposure to sunlight should be minimized as you may be more sensitive to its rays. Ask your doctor before using other medication on the skin, especially anything containing sulfur, resorcinol, or salicylic acid, as the combination may be too irritating. Abrasive soaps and cleansers should be used with caution for the same reason. Side effects can include skin irritation, swelling, lightening or darkening of the skin, an increase in acne sores, excessive redness, and crusted or blistered skin.

Acne vulgaris and its resultant scars have been associated with significant social and academic difficulties that can last into adulthood, including difficulties obtaining employment.[30][177] Until the 1930s, it was largely seen as a trivial problem among middle-class girls – a trivial problem, because, unlike smallpox and tuberculosis, no one died from it, and a feminine problem, because boys were much less likely to seek medical assistance for it.[165] During the Great Depression, dermatologists discovered that young men with acne had difficulty obtaining jobs, and during World War II, some soldiers in tropical climates developed such severe and widespread tropical acne on their bodies that they were declared medically unfit for duty.[165]
A big acne myth is that you can wash it away. Although you should wash your face in the morning to rid it of any bacteria and saliva that might be lingering from your pillow, and you should wash it at night to clean away the sweat and grime that accumulated, twice a day is plenty. You also shouldn’t spend more than 30 seconds on this part of your skin care routine. Begin with warm water that is not too hot. When you are finished, you can splash your face with cold water to close the pores or use an astringent. Make sure you get a clean towel each time you wash so that you aren’t patting more bacteria onto your clean face. If you use a washcloth to clean your face, make sure you don’t reuse it.
Oh, hello old friend. Salicylic acid is the go-to fix for pimply preteens. And cruising through the aisles at the drugstore, you’ll find it as the active ingredient on the majority of products labeled “acne wash” or “spot treatment.” Salicylic acid is a beta-hydroxy acid that works by dissolving excess oil and gently exfoliating away dead skin cells. Salicylic also has anti-inflammatory properties to help with inflamed cystic breakouts that can occur when blockages deep in the hair follicles rupture beneath the skin. It’s best to apply this ingredient as a toner, moisturizer, or leave-on spot treatment instead of a face wash to give it time to do its work. And keep in mind, salicylic acid can dry out the skin if over-applied, so maybe choose only one product with the ingredient to use every day.
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